Journey to the Joint
After FLEXISEQ™ is applied to the skin, the water-based gel begins to dry which triggers the activity of the Sequessome™ vesicles contained within.
A Sequessome™ loves to be surrounded by water and as the water in its surrounding gel evaporates, it seeks out the next closest source of water – below the skin. The super-flexibility of the micro-spheres allows them to squeeze easily between skin cells and travel gently along the natural spaces found between them.
A layer of FLEXISEQ gel contains millions of Sequessome™ vesicles and this great volume of spheres entering the skin drives those already inside even deeper. Subsequently, Sequessome™ vesicles continue travelling to beyond the skin, through underlying tissues and into joints where they populate the watery environment of the synovial fluid.
Sequessome Technology
Osteoarthritic Joint
The Sequessome™ vesicles contained within the joint capsule are attracted to the cartilage and accumulate on the damaged cartilage surfaces creating a “film” of lubricating phospholipids.
Through this action, Sequessome™ vesicles replenish the depleted layer of lubricants otherwise found on healthy cartilage, resulting in proven pain relief and reduction of joint stiffness. Longer term, further deterioration of the cartilage may be slowed.
Benefits of using FLEXISEQ
- Proven pain relief and restoration of joint function.
- Excellent safety profile. The only product related side effects experienced in large trials were minor, transient skin irritations.
- FLEXISEQ is a convenient topical gel.
- No known interactions with drugs and has been used in conjunction with other medications prescribed for the pain associated with osteoarthritis.
Safety
- To date, no serious side effects have been reported that are related to the use of FLEXISEQ.
- In around 1000 patients, roughly one in ten experienced some minor skin irritations most of which disappeared after a few weeks of continued use.